Gene genealogies, variation and evolution : a primer in coalescent theory / Jotun Hein, Mikkel H. Schierup, and Carsten Wiuf.
Material type: TextPublication details: Oxford ; New York : Oxford University Press, [(c)2005.]Description: 1 online resource (xiii, 276 pages) : illustrationsContent type:- text
- computer
- online resource
- 1423770803
- 9781423770800
- 9786610758982
- 6610758980
- Population genetics -- Mathematical models
- Population genetics
- Gene mapping
- Genetics -- Mathematical models
- Genetics, Population
- Chromosome Mapping
- Models, Genetic
- nucleotidenvolgordes
- nucleotide sequences
- dna sequencing
- genetische variatie
- genetic variation
- genetische diversiteit
- genetic diversity
- populatiegenetica
- population genetics
- gegevensanalyse
- data analysis
- waarschijnlijkheidstheorie
- probability theory
- Population and Quantitative Genetics
- Kwantitatieve- en populatiegenetica
- QH438.4.3
- COPYRIGHT NOT covered - Click this link to request copyright permission: https://lib.ciu.edu/copyright-request-form
Item type | Current library | Collection | Call number | URL | Status | Date due | Barcode | |
---|---|---|---|---|---|---|---|---|
Online Book | G. Allen Fleece Library Online | Non-fiction | QH438.4.3 (Browse shelf(Opens below)) | Link to resource | Available | ocm68623837\ |
Includes bibliographies and index.
The basic coalescent -- A Y-chromosome data set -- Data and theory -- The Wright-Fisher model -- Assumptions of the Wright-Fisher model -- The number of descendants of a gene in one generation -- The geometric distribution -- The exponential distribution -- The discrete-time coalescent -- Coalescence of a sample of two genes -- Coalescence of a sample of n genes -- Example: Effect of approximations -- The continuous time coalescent -- Calculating simple quantities on a coalescent tree -- The height of a tree -- The total branch length of a tree -- The effect of sampling more sequences -- The effective population size -- The Moran model -- Robustness of the coalescent -- From genealogies to sequences -- Mathematical models of alleles -- The infinite alleles model -- The infinite sites model -- Finite sites model -- The Wright-Fisher model with mutation -- Algorithms for simulating sequence evolution -- The probability of a sample configuration -- Infinite alleles model -- Infinite sites model -- Impossible ancestral states -- Quantities related to the infinite sites model -- The number of segregating sites -- Haplotypes -- Pairwise mismatch distribution -- Estimators of [theta] and Tajima's D -- Evolutionary versus sampling variance -- Example 1: The variable S[subscript n] -- Example 2: Tajima's estimator [pi] -- Trees and topologies -- Some terminology -- The jump process and the waiting time process -- The coalescent and phylogenetic trees -- Counting trees and topologies -- Gene trees -- How to build a gene tree.
"This text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Authored by leading experts, and rich in examples and illustrations, Gene Genealogies, Variation and Evolution is highly suitable for a graduate course in statistics; population, molecular and medical genetics; and for bioscience and medicine and students studying the evolution of human population and disease. It is also a reference for bioscientists and statisticians in the pharmaceutical industry and academia."--Jacket.
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