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Hemisynthesis of phenolic metabolites

By: Material type: TextTextSeries: Description: 1 online resource (123 pages)Content type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 3736965257
  • 9783736965256
Subject(s): Genre/Form: LOC classification:
  • QK898 .H465 2021
Online resources: Available additional physical forms:
Contents:
Preliminary remarks -- List of abbreviations -- List of publications -- Conferences -- Declaration of contribution as co-author -- Chapter 1 General Introduction -- 1 Polyphenols -- 2 Anthocyanins -- 2.3 Physiological properties -- 3 Synthesis of phase II metabolites -- 3.1 Enzymatic synthesis -- 3.2 Chemical synthesis -- 3.3 Microbial synthesis -- 4 Analysis and Characterization of the metabolites -- 4.1 UV/Vis spectra -- 4.2 Mass spectrometry -- 4.3 Purification -- 5 Aims of the thesis -- Chapter 2 Hemisynthesis of Anthocyanin Phase II Metabolites byPorcine Liver Enzymes
2 Materials and methods -- 2.1 Chemicals -- 2.2 Isolation of anthocyanins -- 2.3 Preparation of liver fractions -- 2.4 Incubation -- 3 Results and discussion -- 3.1 Methylation -- 3.2 Glucuronidation -- 3.3 Sulfation -- 3.4 Multiple Conversions -- 4 References -- Chapter 3 Chemical Hemisynthesis of Sulfated Cyanidin-3-OGlucosideand Cyanidin Metabolites -- 1 Introduction -- 2 Results and discussion -- 2.1 Cyanidin Sulfates -- 2.2 Cyanidin-3-O-Glucoside Sulfates -- 2.3 Challenges -- 2.4 Human Pilot Study -- 3 Materials and methods -- 3.1 Chemicals
3.3 LC-MS-Analysis -- 3.4 Study Design and Analysis of Urine -- 4 Conclusions -- 5 References -- Chapter 4 Methylation of Cyanidin-3-O-Glucoside with DimethylCarbonat e -- 1 Introduction -- 2 Results and discussion -- 2.1 First Observations -- 2.2 Experimental Design -- 2.3 Increase in Solvation of Anthocyanins -- 2.4 Identification -- 3 Materials and methods -- 3.1 Chemicals -- 3.2 Hemisynthesis -- 3.3 LC-MS Analysis -- 4 Conclusion -- 5 References -- Chapter 5 Concluding remarks -- 1 Impact of contributions
3 References -- Summary -- Zusammenfassung -- Acknowledgement
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Item type Current library Collection Call number URL Status Date due Barcode
Online Book (LOGIN USING YOUR MY CIU LOGIN AND PASSWORD) Online Book (LOGIN USING YOUR MY CIU LOGIN AND PASSWORD) G. Allen Fleece Library ONLINE Non-fiction QK898.764 (Browse shelf(Opens below)) Link to resource Available on1286428703

Description based upon print version of record.

Includes bibliographies and index.

Intro -- Preliminary remarks -- List of abbreviations -- List of publications -- Conferences -- Declaration of contribution as co-author -- Chapter 1 General Introduction -- 1 Polyphenols -- 2 Anthocyanins -- 2.3 Physiological properties -- 3 Synthesis of phase II metabolites -- 3.1 Enzymatic synthesis -- 3.2 Chemical synthesis -- 3.3 Microbial synthesis -- 4 Analysis and Characterization of the metabolites -- 4.1 UV/Vis spectra -- 4.2 Mass spectrometry -- 4.3 Purification -- 5 Aims of the thesis -- Chapter 2 Hemisynthesis of Anthocyanin Phase II Metabolites byPorcine Liver Enzymes

1 Introduction -- 2 Materials and methods -- 2.1 Chemicals -- 2.2 Isolation of anthocyanins -- 2.3 Preparation of liver fractions -- 2.4 Incubation -- 3 Results and discussion -- 3.1 Methylation -- 3.2 Glucuronidation -- 3.3 Sulfation -- 3.4 Multiple Conversions -- 4 References -- Chapter 3 Chemical Hemisynthesis of Sulfated Cyanidin-3-OGlucosideand Cyanidin Metabolites -- 1 Introduction -- 2 Results and discussion -- 2.1 Cyanidin Sulfates -- 2.2 Cyanidin-3-O-Glucoside Sulfates -- 2.3 Challenges -- 2.4 Human Pilot Study -- 3 Materials and methods -- 3.1 Chemicals

3.2 Hemisynthesis of Sulfated Metabolites -- 3.3 LC-MS-Analysis -- 3.4 Study Design and Analysis of Urine -- 4 Conclusions -- 5 References -- Chapter 4 Methylation of Cyanidin-3-O-Glucoside with DimethylCarbonat e -- 1 Introduction -- 2 Results and discussion -- 2.1 First Observations -- 2.2 Experimental Design -- 2.3 Increase in Solvation of Anthocyanins -- 2.4 Identification -- 3 Materials and methods -- 3.1 Chemicals -- 3.2 Hemisynthesis -- 3.3 LC-MS Analysis -- 4 Conclusion -- 5 References -- Chapter 5 Concluding remarks -- 1 Impact of contributions

2 Remaining challenges and future directions -- 3 References -- Summary -- Zusammenfassung -- Acknowledgement

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