MARC details
| 000 -LEADER |
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04012cam a22004577i 4500 |
| 001 - CONTROL NUMBER |
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on1311315043 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20230707145938.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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m d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr cnu---unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220416s2022 si o ||| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
EBLCP |
| Language of cataloging |
eng |
| Description conventions |
rda |
| Transcribing agency |
EBLCP |
| Modifying agency |
NT |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9815040375 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9789815040371 |
| Qualifying information |
(electronic) |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
3199724 |
| -- |
(NT) |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
1311315043 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC280.6 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
MAIN |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Melim, Catarina. |
| Relator term |
Author |
| 245 10 - TITLE STATEMENT |
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| Title |
Mixed Polymeric Micelles for Osteosarcoma Therapy |
| Medium |
[electronic resource] |
| 260 #1 - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Singapore : |
| Name of publisher, distributor, etc. |
Bentham Science Publishers, |
| Date of publication, distribution, etc. |
(c)2022. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource (92 pages) |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 500 ## - GENERAL NOTE |
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| General note |
Description based upon print version of record. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographies and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Title |
Cover -- |
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Title -- |
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Copyright -- |
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End User License Agreement -- |
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Contents -- |
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Foreword -- |
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Preface -- |
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DISCLAIMER -- |
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FUNDING -- |
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CONSENT FOR PUBLICATION -- |
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CONFLICT OF INTEREST -- |
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ACKNOWLEDGEMENT -- |
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Abstract -- |
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Introduction -- |
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1. OSTEOSARCOMA -- |
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1.1. Pathophysiology -- |
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1.1.1. Genetic Alterations -- |
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1.2. Diagnosis and Treatment -- |
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1.2.1. Targeted Therapy -- |
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1.2. Challenges to Osteosarcoma Treatment -- |
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1.2.1. Multidrug Resistance -- |
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1.2.2. Active Targeting -- |
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2. RNA INTERFERENCE TECHNOLOGY -- |
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2.1. miRNAs -- |
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2.1. miRNA-145 -- |
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3. GENE THERAPY -- |
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3.1. Viral and Non-viral Vectors |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
3.1.1. Polymeric Micelles -- |
| Title |
3.1.2. Cationic Polymers -- |
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3.1.3. Poloxamers and Poloxamines -- |
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3.1.4. Micelleplexes -- |
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3.1.5. Physicochemical Characterization -- |
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AIMS -- |
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Materials and Methods -- |
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1. MATERIALS -- |
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2. CHITOSAN COMPLEXED WITH PLURONIC® F68 -- |
| -- |
3. CHITOSAN COMPLEXED WITH PLURONICS® F68 AND P123 -- |
| -- |
4. SYNTHESIS OF PLURONIC® F68 DIACRYLATE -- |
| -- |
5. SYNTHESIS OF PLURONIC® F68 DIACRYLATE CONJUGATED WITH PEI (F68-PEI) -- |
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6. CHARACTERIZATION OF THE PREPARED POLYMERIC MICELLES -- |
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6.1. Evaluation of Particle Size and Zeta Potential -- |
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6.2. 1H-NMR Spectroscopy |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
6.3. Fourier-Transform Infrared Spectroscopy -- |
| Title |
6.4. Transmission Electron Microscopy -- |
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6.5. Statistical Analysis -- |
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Results and Discussion -- |
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1. CHITOSAN COMPLEXED WITH PLURONIC® F68 -- |
| -- |
2. CHITOSAN COMPLEXED WITH PLURONICS® F68 AND P123 -- |
| -- |
3. SYNTHESIS OF PLURONIC® F68 DIACRYLATE -- |
| -- |
4. SYNTHESIS OF PLURONIC® F68 DIACRYLATE CONJUGATED WITH PEI -- |
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5. PREPATION OF MIXED PLURONIC® F68-PEI AND PLURONIC® P123 MICELLES -- |
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6. MORPHOLOGICAL CHARACTERIZATION -- |
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Conclusion -- |
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FUTURE PERSPECTIVES -- |
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Annex -- |
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1. CHITOSAN COMPLEXED WITH PLURONIC® F68 |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
2. SYNTHESIS OF PLURONIC® F68 DIACRYLATE CONJUGATED WITH PEI -- |
| Title |
ABBREVIATIONS -- |
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LIST OF ABBREVIATIONS -- |
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REFERENCES -- |
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REFERENCES -- |
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Subject Index -- |
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Back Cover |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Osteosarcoma is a rare bone tumor that has a high incidence among children and young adults. Despite recent therapeutic developments, osteosarcomastill presents major hurdles to achieving successful results, mainly due to the presence of multi-drug-resistant cells.This monograph primarily aims to provide information about the basic science behind the treatment of osteosarcoma along with experimental results for a novel formulation that overcomes multidrug resistance, and therefore, may serve as a viable treatment option. The book starts with an updated and conciseguide to the pathophysiology of the. |
| 530 ## - COPYRIGHT INFORMATION: |
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| COPYRIGHT INFORMATION |
COPYRIGHT NOT covered - Click this link to request copyright permission: |
| Uniform Resource Identifier |
<a href="b">b</a> |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Osteosarcoma |
| General subdivision |
Treatment. |
| 655 ## - INDEX TERM--GENRE/FORM |
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| Genre/form data or focus term |
Electronic Books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Figueiras, Ana. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Jarak, Ivana. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Public note |
|
| Uniform Resource Identifier |
<a href="httpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3199724&site=eds-live&custid=s3260518">httpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3199724&site=eds-live&custid=s3260518</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Online Book |
| DONATED BY: |
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| VENDOR |
EBSCO |
| Classification part |
RC. |
| PUBLICATION YEAR |
2022 |
| LOCATION |
Online |
| REQUESTED BY: |
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NFIC |
| Barecode |
on1311315043 |
| Source of classification or shelving scheme |
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| 994 ## - |
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92 |
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NT |
