MARC details
000 -LEADER |
fixed length control field |
03898cam a22004337i 4500 |
001 - CONTROL NUMBER |
control field |
on1311315043 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OCoLC |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20240726104850.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220416s2022 si o ||| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
EBLCP |
Language of cataloging |
eng |
Description conventions |
rda |
Transcribing agency |
EBLCP |
Modifying agency |
NT |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9815040375 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9789815040371 |
Qualifying information |
|
050 04 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC280 |
Item number |
.M594 2022 |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
MAIN |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Melim, Catarina. |
Relator term |
Author |
245 10 - TITLE STATEMENT |
Title |
Mixed Polymeric Micelles for Osteosarcoma Therapy |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
Singapore : |
Name of publisher, distributor, etc. |
Bentham Science Publishers, |
Date of publication, distribution, etc. |
(c)2022. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 online resource (92 pages) |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
347 ## - DIGITAL FILE CHARACTERISTICS |
File type |
data file |
Source |
rda |
500 ## - GENERAL NOTE |
General note |
Description based upon print version of record. |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc. note |
Includes bibliographies and index. |
505 00 - FORMATTED CONTENTS NOTE |
Formatted contents note |
Cover -- |
Title |
Title -- |
-- |
Copyright -- |
-- |
End User License Agreement -- |
-- |
Contents -- |
-- |
Foreword -- |
-- |
Preface -- |
-- |
DISCLAIMER -- |
-- |
FUNDING -- |
-- |
CONSENT FOR PUBLICATION -- |
-- |
CONFLICT OF INTEREST -- |
-- |
ACKNOWLEDGEMENT -- |
-- |
Abstract -- |
-- |
Introduction -- |
-- |
1. OSTEOSARCOMA -- |
-- |
1.1. Pathophysiology -- |
-- |
1.1.1. Genetic Alterations -- |
-- |
1.2. Diagnosis and Treatment -- |
-- |
1.2.1. Targeted Therapy -- |
-- |
1.2. Challenges to Osteosarcoma Treatment -- |
-- |
1.2.1. Multidrug Resistance -- |
-- |
1.2.2. Active Targeting -- |
-- |
2. RNA INTERFERENCE TECHNOLOGY -- |
-- |
2.1. miRNAs -- |
-- |
2.1. miRNA-145 -- |
-- |
3. GENE THERAPY -- |
-- |
3.1. Viral and Non-viral Vectors |
505 00 - FORMATTED CONTENTS NOTE |
Formatted contents note |
3.1.1. Polymeric Micelles -- |
Title |
3.1.2. Cationic Polymers -- |
-- |
3.1.3. Poloxamers and Poloxamines -- |
-- |
3.1.4. Micelleplexes -- |
-- |
3.1.5. Physicochemical Characterization -- |
-- |
AIMS -- |
-- |
Materials and Methods -- |
-- |
1. MATERIALS -- |
-- |
2. CHITOSAN COMPLEXED WITH PLURONIC F68 -- |
-- |
3. CHITOSAN COMPLEXED WITH PLURONICS F68 AND P123 -- |
-- |
4. SYNTHESIS OF PLURONIC F68 DIACRYLATE -- |
-- |
5. SYNTHESIS OF PLURONIC F68 DIACRYLATE CONJUGATED WITH PEI (F68-PEI) -- |
-- |
6. CHARACTERIZATION OF THE PREPARED POLYMERIC MICELLES -- |
-- |
6.1. Evaluation of Particle Size and Zeta Potential -- |
-- |
6.2. 1H-NMR Spectroscopy |
505 00 - FORMATTED CONTENTS NOTE |
Formatted contents note |
6.3. Fourier-Transform Infrared Spectroscopy -- |
Title |
6.4. Transmission Electron Microscopy -- |
-- |
6.5. Statistical Analysis -- |
-- |
Results and Discussion -- |
-- |
1. CHITOSAN COMPLEXED WITH PLURONIC F68 -- |
-- |
2. CHITOSAN COMPLEXED WITH PLURONICS F68 AND P123 -- |
-- |
3. SYNTHESIS OF PLURONIC F68 DIACRYLATE -- |
-- |
4. SYNTHESIS OF PLURONIC F68 DIACRYLATE CONJUGATED WITH PEI -- |
-- |
5. PREPATION OF MIXED PLURONIC F68-PEI AND PLURONIC P123 MICELLES -- |
-- |
6. MORPHOLOGICAL CHARACTERIZATION -- |
-- |
Conclusion -- |
-- |
FUTURE PERSPECTIVES -- |
-- |
Annex -- |
-- |
1. CHITOSAN COMPLEXED WITH PLURONIC F68 |
505 00 - FORMATTED CONTENTS NOTE |
Formatted contents note |
2. SYNTHESIS OF PLURONIC F68 DIACRYLATE CONJUGATED WITH PEI -- |
Title |
ABBREVIATIONS -- |
-- |
LIST OF ABBREVIATIONS -- |
-- |
REFERENCES -- |
-- |
REFERENCES -- |
-- |
Subject Index -- |
-- |
Back Cover |
520 0# - SUMMARY, ETC. |
Summary, etc. |
Osteosarcoma is a rare bone tumor that has a high incidence among children and young adults. Despite recent therapeutic developments, osteosarcomastill presents major hurdles to achieving successful results, mainly due to the presence of multi-drug-resistant cells.This monograph primarily aims to provide information about the basic science behind the treatment of osteosarcoma along with experimental results for a novel formulation that overcomes multidrug resistance, and therefore, may serve as a viable treatment option. The book starts with an updated and conciseguide to the pathophysiology of the. |
530 ## - COPYRIGHT INFORMATION: |
COPYRIGHT INFORMATION |
COPYRIGHT NOT covered - Click this link to request copyright permission: |
Uniform Resource Identifier |
<a href="b">b</a> |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Osteosarcoma |
General subdivision |
Treatment. |
655 #1 - INDEX TERM--GENRE/FORM |
Genre/form data or focus term |
Electronic Books. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Figueiras, Ana. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Jarak, Ivana. |
856 40 - ELECTRONIC LOCATION AND ACCESS |
-- |
Click to access digital title | log in using your CIU ID number and my.ciu.edu password. |
Uniform Resource Identifier |
<a href="httpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3199724&site=eds-live&custid=s3260518">httpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3199724&site=eds-live&custid=s3260518</a> |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Online Book (LOGIN USING YOUR MY CIU LOGIN AND PASSWORD) |
DONATED BY: |
|
VENDOR |
EBSCO |
Classification part |
RC. |
PUBLICATION YEAR |
2022 |
LOCATION |
ONLINE |
REQUESTED BY: |
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-- |
|
-- |
NFIC |
Source of classification or shelving scheme |
|
994 ## - |
-- |
92 |
-- |
NT |
902 ## - LOCAL DATA ELEMENT B, LDB (RLIN) |
a |
1 |
b |
Cynthia Snell |
c |
1 |
d |
Cynthia Snell |