000 | 02969cam a2200397Ki 4500 | ||
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001 | on1239736316 | ||
003 | OCoLC | ||
005 | 20240726105151.0 | ||
008 | 210225s2021 pau ob 001 0 eng d | ||
040 |
_aNT _beng _erda _epn _cNT _dOCLCO _dEBLCP _dP@U _dJSTOR _dYDX _dTXM _dAAA |
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_a9780822987710 _q((electronic)l(electronic)ctronic) |
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050 | 0 | 4 |
_aQR360 _b.T354 2021 |
049 | _aMAIN | ||
100 | 1 |
_aSankaran, Neeraja, _e1 |
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245 | 1 | 0 |
_aA tale of two viruses : _bparallels in the research trajectories of tumor and bacterial viruses / _cNeeraja Sankaran. |
300 | _a1 online resource | ||
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_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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_aonline resource _bcr _2rdacarrier |
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_adata file _2rda |
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_a"In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny-one of the two types of viral life cycles-which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses-bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer-and the importance of Lwoff's discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell's genetic material indefinitely, or until induced by UV radiation. But until Lwoff's discovery of the mechanism of lysogeny, microbiologist Félix d'Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices"-- _cProvided by publisher. |
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_a2 _ub |
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600 | 1 | 0 |
_aRous, Peyton, _d1879-1970. |
600 | 1 | 0 |
_aLwoff, André, _d1902-1994. |
600 | 1 | 0 | _aD'Herelle, Félix. |
650 | 0 | _aViruses. | |
650 | 0 | _aBacteriophages. | |
650 | 0 | _aSarcoma. | |
650 | 0 |
_aVirology _xResearch. |
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655 | 1 | _aElectronic Books. | |
856 | 4 | 0 |
_uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2752465&site=eds-live&custid=s3260518 _zClick to access digital title | log in using your CIU ID number and my.ciu.edu password |
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_cOB _D _eEB _hQR _m2021 _QOL _R _x _8NFIC _2LOC |
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_c91247 _d91247 |
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_a1 _bCynthia Snell _c1 _dCynthia Snell |