000 02969cam a2200397Ki 4500
001 on1239736316
003 OCoLC
005 20240726105151.0
008 210225s2021 pau ob 001 0 eng d
040 _aNT
_beng
_erda
_epn
_cNT
_dOCLCO
_dEBLCP
_dP@U
_dJSTOR
_dYDX
_dTXM
_dAAA
020 _a9780822987710
_q((electronic)l(electronic)ctronic)
050 0 4 _aQR360
_b.T354 2021
049 _aMAIN
100 1 _aSankaran, Neeraja,
_e1
245 1 0 _aA tale of two viruses :
_bparallels in the research trajectories of tumor and bacterial viruses /
_cNeeraja Sankaran.
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
504 _a2
520 0 _a"In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny-one of the two types of viral life cycles-which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses-bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer-and the importance of Lwoff's discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell's genetic material indefinitely, or until induced by UV radiation. But until Lwoff's discovery of the mechanism of lysogeny, microbiologist Félix d'Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices"--
_cProvided by publisher.
530 _a2
_ub
600 1 0 _aRous, Peyton,
_d1879-1970.
600 1 0 _aLwoff, André,
_d1902-1994.
600 1 0 _aD'Herelle, Félix.
650 0 _aViruses.
650 0 _aBacteriophages.
650 0 _aSarcoma.
650 0 _aVirology
_xResearch.
655 1 _aElectronic Books.
856 4 0 _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2752465&site=eds-live&custid=s3260518
_zClick to access digital title | log in using your CIU ID number and my.ciu.edu password
942 _cOB
_D
_eEB
_hQR
_m2021
_QOL
_R
_x
_8NFIC
_2LOC
994 _a92
_bNT
999 _c91247
_d91247
902 _a1
_bCynthia Snell
_c1
_dCynthia Snell