000			03323cam a2200433 i 4500
001			on1024312636
003			OCoLC
005			20240726105055.0
008			180226t20182018maua ob 001 0 eng d
040			_aNT _beng _erda _epn _cNT _dYDX _dEBLCP _dIUL _dZCU _dNAM _dUAB _dOCLCO _dOCLCQ _dOCLCO _dDEGRU _dOCLCF _dMYG _dOCLCA _dBRX _dDKU _dOCLCO _dKMS _dFVL _dOCLCO _dNRC _dOCLCO _dOCLCQ _dJF0 _dOCLCQ _dOCLCA _dVLY _dOCLCQ _dCOH _dK6U _dJSTOR
020			_a9780674984721 _q((electronic)l(electronic)ctronic)
020			_a9780674984738
050	0	4	_aQL537 _b.F577 2018
049			_aMAIN
100	1		_aMohr, Stephanie Elizabeth, _d1971- _e1
245	1	0	_aFirst in fly : _bDrosophila research and biological discovery / _cStephanie Elizabeth Mohr.
260			_aCambridge, Massachusetts : _bHarvard University Press, _c(c)2018.
300			_a1 online resource (xii, 257 pages) : _billustrations
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_adata file _2rda
520	0		_aA single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. This book notes insights uncovered by investigators using this model organism. The author draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.-- _cProvided by publisher
504			_a2
505	0	0	_aMaps -- _tChange -- _tCommunication -- _tSize -- _tDirection -- _tDifference -- _tDefenses -- _tBehavior -- _tCoordination -- _tContinuity.
530			_a2 _ub
650		0	_aDrosophila melanogaster _xGenetics.
650		0	_aDrosophila melanogaster _xPhysiology.
650		0	_aAnimal models in research.
650	1	2	_aDrosophila melanogaster _xgenetics.
650	1	2	_aDrosophila melanogaster _xphysiology.
650	1	2	_aDrosophila Proteins.
650	2	2	_aModels, Animal.
655		1	_aElectronic Books.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1712993&site=eds-live&custid=s3260518 _zClick to access digital title | log in using your CIU ID number and my.ciu.edu password
942			_cOB _D _eEB _hQL. _m2018 _QOL _R _x _8NFIC _2LOC
994			_a92 _bNT
999			_c88116 _d88116
902			_a1 _bCynthia Snell _c1 _dCynthia Snell