000			03326cam a2200409Mi 4500
001			on1036781636
003			OCoLC
005			20240726105052.0
008			180519s2018 nju o 000 0 eng d
040			_aEBLCP _beng _erda _cEBLCP _dJSTOR _dCNCGM _dOCLCF _dIDB _dNT
020			_a9781400890064 _q((electronic)l(electronic)ctronic)
050	0	4	_aTP248 _b.M654 2018
049			_aMAIN
100	1		_aZocchi, Giovanni. _e1
245	1	0	_aMolecular machines _ba materials science approach / _cGoivanni Zocchi.
260			_aPrinceton : _bPrinceton University Press, _c(c)2018.
300			_a1 online resource (189 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_adata file _2rda
500			_aDescription based upon print version of record.
504			_a2
505	0	0	_aCover; Title; Copyright; CONTENTS; Preface; Acknowledgments; Dedication; 1 Brownian Motion; 1.1 Random Walk; 1.2 Polymer as a Simple Random Walk; 1.3 Direct Calculation of p(R); 1.4 The Langevin Approach; 1.5 Correlation Functions; 1.6 Barrier Crossing; 1.7 What is Equilibrium?; 2 Statics of DNA Deformations; 2.1 Introduction; 2.2 DNA Melting; 2.3 Zipper Model; 2.4 Experimental Melting Curves; 2.5 Base Pairing and Base Stacking as Separate Degrees of Freedom; 2.6 Hamiltonian Formulation of the Zipper Model; 2.7 2 × 2Model: Cooperativity from Local Rules; 2.8 Nearest Neighbor Model
505	0	0	_a2.9 Connection to Nonlinear Dynamics2.10 Linear and Nonlinear Elasticity of DNA; 2.11 Bending Modulus and Persistence Length; 2.12 Measurements of DNA Elasticity: Long Molecules; 2.13 Measurements of DNA Elasticity: Short Molecules; 2.14 The Euler Instability; 2.15 The DNA Yield Transition; 3 Kinematics of Enzyme Action; 3.1 Introduction; 3.2 Michaelis-Menten Kinetics; 3.3 The Method of the DNA Springs; 3.4 Force and Elastic Energy in the Enzyme-DNA Chimeras; 3.5 Injection of Elastic Energy vs. Activity Modulation; 3.6 Connection to Nonlinear Dynamics: Two Coupled Nonlinear Springs
505	0	0	_a4 Dynamics of Enzyme Action4.1 Introduction; 4.2 Enzymes are Viscoelastic; 4.3 Nonlinearity of the Enzyme's Mechanics; 4.4 Timescales; 4.5 Enzymatic Cycle and Viscoelasticity: Motors; 4.6 Internal Dissipation; 4.7 Origin of the Restoring Force g; 4.8 Models Based on Chemical Kinetics (Fisher and Kolomeisky, 1999); 4.9 Different Levels of Microscopic Description; 4.10 Connection to Information Flow; 4.11 Normal Mode Analysis; 4.12 Many States of the Folded Protein: Spectroscopy; 4.13 Interesting Topics in Nonequilibrium Thermodynamics Relating to Enzyme Dynamics; Bibliography
505	0	0	_aChapter 1: Brownian MotionChapter 2: Statics of DNA Deformations; Chapter 3: Kinematics of Enzyme Action; Chapter 4: Dynamics of Enzyme Action; Index
530			_a2 _ub
650		0	_aMolecular machinery.
650		0	_aNanoscience.
650		0	_aNanotechnology.
655		1	_aElectronic Books.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1682203&site=eds-live&custid=s3260518 _zClick to access digital title | log in using your CIU ID number and my.ciu.edu password
942			_cOB _D _eEB _hTP.. _m2018 _QOL _R _x _8NFIC _2LOC
994			_a92 _bNT
999			_c88007 _d88007
902			_a1 _bCynthia Snell _c1 _dCynthia Snell