000 03051cam a2200457Mi 4500
001 ocn902958215
003 OCoLC
005 20240726104938.0
008 150207s2015 nju o 000 0 eng d
040 _aEBLCP
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020 _a9781400868223
_q((electronic)l(electronic)ctronic)
050 0 4 _aQH431
_b.H937 2015
049 _aMAIN
100 1 _aEphrussi, Boris,
_d1901-1979.
_e1
245 1 0 _aHybridization of Somatic Cells.
260 _aPrinceton :
_bPrinceton University Press,
_c(c)2015.
300 _a1 online resource (187 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
490 1 _aPrinceton Legacy Library
504 _a2
520 0 _aSince its discovery in I960, the hybridization of somatic cells has evolved from a biological curiosity into an analytical method that today underlies nearly all investigations of the genetic aspects of various biological phenomena. As an eyewitness to this development from its inception forward, Boris Ephrussi here relates the history of somatic hybridization and the formation of its methodology, lie follows with a discussion of the characteristics and properties of the resultant hybrid cells. Together, these topics comprise an authoritative introduction to the principles of the technique.
505 0 0 _tFrontmatter --
_tPreface --
_tContents --
_tCHAPTER 1. Introduction --
_tCHAPTER 2. History of Somatic Hybridization --
_tCHAPTER 3. Application of Cell Hybridization to the Study of Formal Genetics --
_tCHAPTER 4. Preliminary Technical and Theoretical Remarks on the Study of Cell Differentiation In Vitro --
_tCHAPTER 5. Application of Cell Hybridization to the Study of Differentiation: I. Reactivation of Nuclei of Differentiated Cells in Heterokaryons --
_tCHAPTER 6. Application of Cell Hybridization to the Study of Differentiation: II. The Fate of Luxury Functions in Somatic Hybrids --
_tCHAPTER 7. Application of Cell Hybridization to the Study of Cancer --
_tCHAPTER 8. Concluding Remarks and Postscript --
_tAppendix --
_tReferences --
_tAuthor Index --
_tSubject Index.
530 _a2
_ub
650 0 _aSomatic hybrids.
650 0 _aCell hybridization.
650 0 _aCytogenetics.
650 0 _aCell culture.
650 0 _aBiology.
650 0 _aCells.
650 0 _aAnatomy.
650 0 _aLife sciences.
650 0 _aPhysical sciences.
655 1 _aElectronic Books.
856 4 0 _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=946816&site=eds-live&custid=s3260518
_zClick to access digital title | log in using your CIU ID number and my.ciu.edu password
942 _cOB
_D
_eEB
_hQH .
_m2015
_QOL
_R
_x
_8NFIC
_2LOC
994 _a92
_bNT
999 _c83713
_d83713
902 _a1
_bCynthia Snell
_c1
_dCynthia Snell