000			03297cam a2200421Mi 4500
001			on1286428703
003			OCoLC
005			20240726104846.0
008			211127s2021 gw o ||| 0 eng d
040			_aEBLCP _beng _erda _cEBLCP _dSFB _dOCLCQ _dOCLCF _dNT
020			_a3736965257
020			_a9783736965256 _q((electronic)l(electronic)ctronic)
050	0	4	_aQK898 _b.H465 2021
049			_aMAIN
100	1		_aStraßmann, Sarah. _e1
245	1	0	_aHemisynthesis of phenolic metabolites
300			_a1 online resource (123 pages).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_adata file _2rda
490	1		_aSchriftenreihe der Professur für Molekulare Lebensmitteltechnologie ; _vv.10
500			_aDescription based upon print version of record.
504			_a2
505	0	0	_aIntro -- _tPreliminary remarks -- _tList of abbreviations -- _tList of publications -- _tConferences -- _tDeclaration of contribution as co-author -- _tChapter 1 General Introduction -- _t1 Polyphenols -- _t2 Anthocyanins -- _t2.3 Physiological properties -- _t3 Synthesis of phase II metabolites -- _t3.1 Enzymatic synthesis -- _t3.2 Chemical synthesis -- _t3.3 Microbial synthesis -- _t4 Analysis and Characterization of the metabolites -- _t4.1 UV/Vis spectra -- _t4.2 Mass spectrometry -- _t4.3 Purification -- _t5 Aims of the thesis -- _tChapter 2 Hemisynthesis of Anthocyanin Phase II Metabolites byPorcine Liver Enzymes
505	0	0	_a1 Introduction -- _t2 Materials and methods -- _t2.1 Chemicals -- _t2.2 Isolation of anthocyanins -- _t2.3 Preparation of liver fractions -- _t2.4 Incubation -- _t3 Results and discussion -- _t3.1 Methylation -- _t3.2 Glucuronidation -- _t3.3 Sulfation -- _t3.4 Multiple Conversions -- _t4 References -- _tChapter 3 Chemical Hemisynthesis of Sulfated Cyanidin-3-OGlucosideand Cyanidin Metabolites -- _t1 Introduction -- _t2 Results and discussion -- _t2.1 Cyanidin Sulfates -- _t2.2 Cyanidin-3-O-Glucoside Sulfates -- _t2.3 Challenges -- _t2.4 Human Pilot Study -- _t3 Materials and methods -- _t3.1 Chemicals
505	0	0	_a3.2 Hemisynthesis of Sulfated Metabolites -- _t3.3 LC-MS-Analysis -- _t3.4 Study Design and Analysis of Urine -- _t4 Conclusions -- _t5 References -- _tChapter 4 Methylation of Cyanidin-3-O-Glucoside with DimethylCarbonat e -- _t1 Introduction -- _t2 Results and discussion -- _t2.1 First Observations -- _t2.2 Experimental Design -- _t2.3 Increase in Solvation of Anthocyanins -- _t2.4 Identification -- _t3 Materials and methods -- _t3.1 Chemicals -- _t3.2 Hemisynthesis -- _t3.3 LC-MS Analysis -- _t4 Conclusion -- _t5 References -- _tChapter 5 Concluding remarks -- _t1 Impact of contributions
505	0	0	_a2 Remaining challenges and future directions -- _t3 References -- _tSummary -- _tZusammenfassung -- _tAcknowledgement
530			_a2 _ub
650		0	_aPolyphenols.
650		0	_aMetabolites.
650		0	_aAnthocyanins.
655		1	_aElectronic Books.
856	4	0	_zClick to access digital title | log in using your CIU ID number and my.ciu.edu password. _uhttpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3104507&site=eds-live&custid=s3260518
942			_cOB _D _eEB _hQK. _m2021 _QOL _R _x _8NFIC _2LOC
994			_a92 _bNT
999			_c80760 _d80760
902			_a1 _bCynthia Snell _c1 _dCynthia Snell