000			04192cam a2200469Ii 4500
001			ocn873818183
003			OCoLC
005			20240726104714.0
008			140318t20142014enka ob 001 0 eng d
010			_a2014427152
040			_aCaPaEBR _beng _erda _epn _cBWS _dOCLCO _dYDXCP _dNT _dCOO _dMMU _dOCLCF _dOCL _dOSU _dEBLCP _dTLS _dDEBSZ _dOCLCQ _dUAB _dOTZ _dOCLCQ _dOCLCO _dOCLCA _dOCLCQ _dM8D _dUKAHL _dNZHMA _dOCLCQ _dVT2 _dOCLCO
016	7		_a016598615 _2Uk
016	7		_a101631570 _2DNLM
020			_a9781908230959 _q((electronic)l(electronic)ctronic)
050	0	4	_aQP625 _b.N498 2014
049			_aMAIN
245	1	0	_aNext-generation sequencing : _bcurrent technologies and applications / _cedited by Jianpin Xu, Department of Biology, McMaster University, Hamilton, ON, Canada.
260			_aNorfolk : _bCaister Academic Press, _c(c)2014.
300			_a1 online resource (xi, 159 pages) : _bcolor illustrations
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_adata file _2rda
520	0		_a"High-throughput, next-generation sequencing (NGS) technologies are capable of producing a huge amount of sequence data in a relatively short time and have revolutionized genome research in recent years. The powerful and flexible nature of NGS has made it an indispensable tool for a broad spectrum of biological sciences and NGS technologies have transformed scientific research in many fields. Written by experts from around the world, this book explores the most recent advances in NGS instrumentation and data analysis. The book begins with a comprehensive description of current NGS platforms, their sequencing chemistries, instrument specifications, and general workflows and procedures. A separate chapter is dedicated to low-quantity, single molecule sequencing technology. Further chapters explore the application of NGS technologies in various fields including polymorphism detection, sRNA research, rare variant detection, large variant detection, exome sequencing, plant development studies, microbial metagenomics, and studies on the human microbiome"--Publisher's description.
504			_a2
505	0	0	_aAn overview of next-generation genome sequencing platforms / _rChandra Shekhar Pareek -- _tAttomole-level genomics with single-molecule direct DNA, cDNA and RNA sequencing technologies / _rFatih Ozsolak -- _tSNP assessment on draft genomes from next generation sequencing data / _rMichael Piechotta and Christoph Dieterich -- _tProcessing large-scale small RNA datasets in Silico / _rDaniel Mapleson, Irina Mohorianu, Helio Pais, Matthew Stocks, Leighton Folkes and Vincent Moulton -- _tUtility of high throughput sequence data in rare variant detection / _rViacheslav Y. Fofanov, Tudor Constantin, Heather Koshinsky and Eureka Genomics -- _tDetecting break points of insertions and deletions from paired-end short reads / _rKai Ye and Zemin Ning -- _tNovel insights from re-sequencing of human exomes through NGS / _rJun Li, Tao Jiang, Xu Yang and Jun Wang -- _tInsights on plant development using NGS technologies / _rYing Wang and Yuling Jiao -- _tNext generation sequencing and the future of microbial metagenomics / _rAndreas Wilke, Peter Larsen and Jack A Gilbert -- _tNext generation sequencing, metagenomes and the human microbiome / _rKaren E. Nelson, Ramana Madupu, Sebastian Szpakowski, Johannes Goll, Konstantinos Krampis and Barbara A. Methé.
530			_a2 _ub
650		0	_aNucleotide sequence.
650		0	_aBioinformatics.
650		0	_aSequence alignment (Bioinformatics)
650		0	_aSequential analysis.
650		0	_aComputational biology.
650	1	2	_aHigh-Throughput Nucleotide Sequencing
653			_aDNA sequencing
653			_aGene mapping
655		1	_aElectronic Books.
700	1		_aXu, Jianping _c(Professor of Biology), _d1965- _e5
856	4	0	_zClick to access digital title | log in using your CIU ID number and my.ciu.edu password. _uhttpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=760283&site=eds-live&custid=s3260518
942			_cOB _D _eEB _hQP. _m2014 _QOL _R _x _8NFIC _2LOC
994			_a92 _bNT
999			_c75502 _d75502
902			_a1 _bCynthia Snell _c1 _dCynthia Snell