000 | 03710cam a2200505 i 4500 | ||
---|---|---|---|
001 | on1125157391 | ||
003 | OCoLC | ||
005 | 20240725203635.0 | ||
008 | 191026s2019 sz a b 000 0 eng | ||
016 | 7 |
_a101760529 _2DNLM |
|
020 |
_a3030118118 _q(pa(print & electronic)rback) |
||
020 |
_a9783030118112 _q(pa(print & electronic)rback) |
||
029 | 0 |
_aNLM _b101760529 |
|
035 | _a(OCoLC)1125157391 | ||
040 |
_aNLM _beng _erda _cNLM _dBDX _dSOI _dOHX _dS2H _dOCLCO _dOCLCF _dOCLCA _dYDX _dOCLCO _dSBI |
||
042 | _apcc | ||
049 | _aSBIM | ||
050 | 0 | 4 | _aRC268.Z69.M654 2019 |
245 | 0 | 0 |
_aMolecular and cell biology of cancer : _bwhen cells break the rules and hijack their own planet / _cRita Fior, Rita Zilhao, editors. _hPR |
260 |
_aCham, Switzerland : _bSpringer, _c(c)2019. |
||
300 |
_aix, 216 pages : _bcolor illustrations ; _c24 cm. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_aunmediated _bn _2rdamedia |
||
338 |
_avolume _bnc _2rdacarrier |
||
490 | 1 |
_aLearning materials in biosciences, _x2509-6125 |
|
504 | _a1 | ||
505 | 0 | 0 |
_aCancer-when cells break the rules and hijack their own planet / _rRita Fior -- _tCancer as an evolutionary process / _rLilia Perfeito -- _tCell signaling in cancer / _rJoao T. Barata and Mariana L. Oliveiera -- _tThe cell cycle, cytoskeleton and cancer / _rIrina S. Fonseca and Monica Bettencourt-Dias -- _tGenomic instability: DNA repair and cancer / _rAna Rita Carlos -- _tCell metabolism in cancer: an energetic switch / _rInes Pimenta de Castro -- _tCancer immunoediting and hijacking of the immune system / _rVanda Povoa and Rita Fior -- _tAngiogenesis-vessels recruitment by tumor cells / _rAna Magalhaes and Sergio Dias -- _tTumor niche disruption and metastatis: the role of Epithelial-Mesenchymal Transition (EMT) / _rRita Zilhao and Helia Neves -- _tCase studies: molecular pathology perspective and impact on oncologic patients' management / _rMireia Castillo-Martin and Joana Bibeiro. |
520 | 0 | _aThis textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg "Hallmarks of Cancer" are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book's closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease. | |
530 |
_a2 _ub |
||
650 | 0 |
_aCancer _xMolecular aspects. |
|
650 | 0 |
_aCancer _xResearch. |
|
650 | 0 | _aCytology. | |
650 | 0 | _aHuman genetics. | |
650 | 0 | _aMetabolism. | |
650 | 0 | _aMolecular biology. | |
650 | 1 | 2 | _aCell Transformation, Neoplastic |
655 | 0 | _aBioMed | |
655 | 0 | _aNursing | |
700 | 1 | _aFior, Rita, | |
700 | 1 | _aZilhao, Rita, | |
700 | 1 | _e5 | |
700 | 1 | _e5 | |
830 | 0 |
_aLearning materials in biosciences. _x2509-6133 |
|
942 |
_cBK _eGOBI _hRC _i2021-2022 _k115.39 _m2019 _nNURS _RNURSING DEPARTMENT _O349620 _2ddc |
||
999 |
_c4488 _d4488 |
||
902 |
_a1 _bCynthia Snell _c1 _dCynthia Snell |