Henry's clinical diagnosis and management by laboratory methods.

Includes bibliographies and index.

Part 1: The clinical laboratory

General concepts and administrative issues -- Optimizing laboratory workflow and performance -- Preanalysis -- Analysis: principles of instrumentation -- Mass spectrometry and applications -- Analysis: clinical laboratory automation -- Point-of-care testing and physician office laboratories -- Postanalysis: medical decision making -- Interpreting laboratory results -- Laboratory statistics -- Quality control -- Clinical laboratory informatics -- Financial management -- Ethics in laboratory medicine

Part 2: Clinical chemistry

Evaluation of renal function, water , electrolytes and acid-base function -- Biochemical markers of bone metabolism -- Carbohydrates -- Lipids and dyslipoproteinemia -- Cardiac injury, atherosclerosis, and thrombotic disease -- Specific proteins -- Clinical enzymology -- Evaluation of liver function -- Laboratory diagnosis of gastrointestinal and pancreatic disorders -- Toxicology and therapeutic drug monitoring -- Evaluation of endocrine function -- Reproductive function and pregnancy -- Vitamins and trace elements -- Chemical basis for analyte assays and common interferences

Part 3: Urine and other body fluids

Basic examination of urine -- Cerebrospinal, synovial, serous body fluids, and alternative specimens

Part 4: Hematology and transfusion medicine

Basic examination of blood and bone marrow -- Hematopoiesis -- Erythrocytic disorders -- Leukocytic disorders -- The flow cytometric evaluation for hematopoietic neoplasia -- Immunohematology -- Transfusion medicine -- Hemapheresis -- Tissue banking and progenitor cells

Part 5: Hemostasis and thrombosis

Coagulation and fibrinolysis -- Platelet disorders and von willebrand disease -- Laboratory approach to thrombotic risk -- Antithrombotic therapy

Part 6: Immunology and immunopathology

Overview of the immune system and immunologic disorders -- Immunoassays and immunochemistry -- Laboratory evaluation of the cellular immune system -- Laboratory evaluation of immunoglobulin function and humoral immunity -- Mediators of inflammation: complement -- Mediators of inflammation: cytokines and adhesion molecules -- Human leukocyte antigen: the major histocompatibility complex of man -- The major histocompatibility complex and disease -- Immunodeficiency disorders -- Clinical and laboratory evaluation of systemic autoimmune rheumatic diseases -- Vasculitis -- Organ-specific autoimmune diseases -- Allergic diseases

Part 7: Medical microbiology

Medical bacteriology -- In vitro testing of antimicrobial agents -- Mycobacteria -- Mycotic diseases -- Spirochete infections -- Chlamydial and mycoplasmal infections -- Rickettsiae and other related intracellular bacteria -- Viral infections -- Medical parasitology -- Specimen collection and handling for diagnosis of infectious diseases

Part 8: Molecular pathology

Introduction to molecular pathology -- Molecular diagnostics: basic principles and techniques -- Polymerase chain reaction and other nucleic acid amplification technology -- Hybridization array technologies -- Applications of cytogenetics in modern pathology -- Molecular diagnosis of genetic diseases -- Molecular genetics of neuro-psychiatric disorders: current research and perspectives -- Identity testing: use of DNA analysis in parentage, forensic, and missing persons testing -- Pharmacogenomics and personalized medicine

Part 9: Clinical pathology of cancer

Diagnosis and management of cancer using serologic and other body fluid markers -- Oncoproteins and early tumor detection -- Molecular diagnosis of hematopoietic neoplasms -- Molecular genetic pathology of solid tumors -- High-throughput genomic and proteomic technologies in the post-genomic era -- Appendices. Physiologic solutions, buffers, acid-base indicators, standard reference materials, and temperature conversions -- Desirable weights, body surface area, and body mass indexApproximations of total blood volume -- Periodic table of elements -- SI units -- Common chimeric genes identified in human malignancies -- Disease/organ panels -- Guidelines for ordering blood for elective surgery.

"This twenty-fourth edition marks more than 100 years since A Manual of Clinical Diagnosis, authored by James Campbell Todd, was introduced in 1908. In its current format as Henry's Clinical Diagnosis and Management by Laboratory Methods, this textbook remains the authoritative source of information for residents, students, and other trainees in the disciplines of clinical pathology and laboratory medicine, and for physicians and laboratory practitioners. The current edition continues the tradition of partnership between laboratory examinations and the formulation and confirmation of clinical diagnoses followed by monitoring of body functions, therapeutic drug levels, other results of medical treatments, and risk assessment for disease"--Publisher's description.

COPYRIGHT: covered - CIU has obtained rights for you to copy and share this title in electronic or print format with students, faculty, and staff.