Neurobiology of Abnormal Emotion and Motivated Behaviors : Integrating Animal and Human Research / edited by Susan Sangha and Dan Foti.

Includes bibliographies and index.

Front Cover; Neurobiology of Abnormal Emotion and Motivated Behaviors; Copyright Page; Contents; List of Contributors; Introduction Emotion and Motivated Behaviors: Integrating Animal and Human Neurobiology Research; Section 1: Emotion-Related Impulsivity Across Disorders and Species; Section 2: Impulsivity and Stress in Eating Disorders; Section 3: Interaction of Stress and Drug-Seeking; Section 4: Learning to Inhibit the Fear Response; Section 5: Abnormal Emotional Reactivity Versus Regulation Across Disorders; I. Emotion-Related Impulsivity Across Disorders and Species.

1 Using Preclinical Models to Understand the Neural Basis of Negative UrgencyIntroduction; Current Models of Negative Urgency; Human Models; Animal Models; Neurobiological Mechanisms of Negative Urgency; Future Directions; Highlights; Acknowledgment; References; Further Reading; 2 Emotion-Related Impulsivity and the Mood Disorders; Introduction; Measures of Emotion-Related Impulsivity; Initial Validation and Links to Psychopathology; Toward a Model of Emotion-Related Impulsivity in Mood Disorders; Depression; Bipolar Disorder; Suicidality and Self-Harm; Summary.

Possible Mechanisms: The Role of Response InhibitionUnanswered Questions; Future Directions; Highlights; References; Further Reading; II. Impulsivity and Stress in Eating Disorders; 3 Impulsivity, Stress Reactivity, and Eating Disorders; Introduction; Current Models; Impulsivity and Binge Eating; Negative Urgency and Binge Eating; Mechanisms; Negative Urgency and Expectancies: Expectancies as a Cognitive Representation of Prepotent Response; Neurobiological Underpinnings of Negative Urgency; Future Directions; Highlights; References; Further Reading.

4 The Genetic Diathesis of Eating Disorders: Critical Roles for Puberty and Ovarian HormonesIntroduction; Current Models: Humans; Eating Disorder Definitions; Mechanisms; Genetic Risk Factors; Age Changes in Genetic Risk; Pubertal Differences in Genetic Risk; Effects of Ovarian Hormones; Animal Models; Future Directions; Highlights; References; 5 Animal Models of Behavioral and Neuroendocrine Components of Eating Disorders; Introduction; Anorexia Nervosa; Bulimia Nervosa; Binge Eating Disorder; Current Models: Eating Disorders, Stress, and Anxiety; Anorexia Nervosa: Diet Restriction Model.

Anorexia Nervosa: Activity-Based AnorexiaAnimal Models of Bulimia Nervosa and Binge Eating Disorder; Bingeing: Intermittent Access Model; Bingeing: Diet and Stress Model; Bingeing: Chronic Subordination Stress Model; Purging: Sham-Feeding Model; Bingeing: Gastric Distension Model; Mechanisms: Neurobiology of Eating Disorders, Stress, and Anxiety; Eating Disorders and Anxiety; Anorexia Nervosa (AN) and Stress; Binge Eating Disorders (BEDs) and Stress; Highlights and Future Directions; References; 6 A Framework for Elucidating Causes and Consequences of Malnutrition in Anorexia Nervosa.

Pulls together world-renowned leaders from both animal and human research, providing a conceptual framework on how neuroscience can inform our understanding of emotion and motivation, while also outlining methodological commonalities between animal and human neuroscience research, with an emphasis on experimental design, physiological recording techniques and outcome measures. Typically, researchers investigating the neurobiology of emotions focus on either animal models or humans. This book brings the two disciplines together to share information and collaborate on future experimental techniques, physiological measures and clinical outcomes.

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