Immunity /William E. Paul.
- Baltimore : Johns Hopkins University Press, (c)2015.
- 1 online resource (xiii, 260 pages)
Includes bibliographies and index.
Part 1. Immunology. Defense and Danger -- Tracing an Immune Response -- The Laws of Immunology: Universality, Tolerance, and Appropriateness -- Growing Up and Learning Immunology. Part 2. The First Law: Universality. Vaccines and Serum Therapy -- How Is Specificity Achieved? -- Immunology's "Eureka": Clonal Selection -- How Does Each Lymphocyte Develop a Distinct Receptor? -- B Cells and T Cells Recognize Different Types of Antigens -- My Foray into the Specificity Problem -- Genes And Immune Response -- The Laboratory of Immunology and the T-Cell Receptor. Part 3. The Second Law: Tolerance -- What Is Tolerance? -- How Does Tolerance Develop? -- Regulatory T Cells and the Prevention of Autoimmunity. Part 4. The Third Law: Appropriateness -- Different Structures, Different Functions -- Specific Types of Infections, Specific Types of T-Cell Responses -- Our Discovery of IL-4 and the Cells That Make It -- CD8 T Cells: Killer Cells and Friends -- Dendritic Cells: The Cells That Interpret the Infectious Threat. Part 5. How Did The Immune System Evolve? -- An "Ancient" Immune Response Controls "Modern" Immunity -- The Microbiome and Innate Immunity -- Evolution of the Immune System and Innate Lymphoid Cells. Part 6. AIDS, Autoimmunity, Allergy, Cancer, and Transplantation -- The HIV Epidemic and the Office Of AIDS Research -- How the Immune System Causes Rheumatoid Arthritis and Lupus -- Allergy and Asthma -- Interleukin-4 and Allergy -- Can the Immune System Control Cancer? -- New Parts for Old: Bone Marrow and Organ Transplantation -- Julien.
9781421418025
Immunity. Immune system. Immunologic diseases. Immune System Diseases--immunology. Immunity. Immune System Phenomena.