TY  - BOOK
AU  - Ephrussi,Boris
TI  - Hybridization of Somatic Cells
T2  - Princeton Legacy Library
SN  - 9781400868223
AV  - QH431 .H937 2015
PY  - 2015///
CY  - Princeton
PB  - Princeton University Press
KW  - Somatic hybrids
KW  - Cell hybridization
KW  - Cytogenetics
KW  - Cell culture
KW  - Biology
KW  - Cells
KW  - Anatomy
KW  - Life sciences
KW  - Physical sciences
KW  - Electronic Books
N1  - 2; Frontmatter --; Preface --; Contents --; CHAPTER 1. Introduction --; CHAPTER 2. History of Somatic Hybridization --; CHAPTER 3. Application of Cell Hybridization to the Study of Formal Genetics --; CHAPTER 4. Preliminary Technical and Theoretical Remarks on the Study of Cell Differentiation In Vitro --; CHAPTER 5. Application of Cell Hybridization to the Study of Differentiation: I. Reactivation of Nuclei of Differentiated Cells in Heterokaryons --; CHAPTER 6. Application of Cell Hybridization to the Study of Differentiation: II. The Fate of Luxury Functions in Somatic Hybrids --; CHAPTER 7. Application of Cell Hybridization to the Study of Cancer --; CHAPTER 8. Concluding Remarks and Postscript --; Appendix --; References --; Author Index --; Subject Index; 2; b
N2  - Since its discovery in I960, the hybridization of somatic cells has evolved from a biological curiosity into an analytical method that today underlies nearly all investigations of the genetic aspects of various biological phenomena. As an eyewitness to this development from its inception forward, Boris Ephrussi here relates the history of somatic hybridization and the formation of its methodology, lie follows with a discussion of the characteristics and properties of the resultant hybrid cells. Together, these topics comprise an authoritative introduction to the principles of the technique
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