The Evolution of Radionanotargeting Towards Clinical Precision Oncologya festschrift in honor of Kalevi Kairemo.
- UAE : Bentham Science Publishers, (c)2022.
- 1 online resource (527 pages)
Description based upon print version of record. DIAGNOSTICS OF PANCREATIC DUCTAL ADENOCARCINOMA WITH RADIOLABELLED NEUROTENSIN ANALOGUES: PRECLINICAL DATA.
Cover -- Tilte -- Copyright -- License -- Contents -- Foreword -- REFERENCES -- Preface -- List of Contributors -- Molecular Imaging in the Development of Antibody-Drug Conjugates -- Clare Senko1,2, Sze-Ting Lee1,2,4,5,*, Hui K. Gan1,3,4, Umbreen Hafeez1,3,4, Sagun Parakh1,3,4 and Andrew M. Scott1,2,4,5 -- INTRODUCTION -- ANTIBODY-DRUG CONJUGATES AS A CANCER THERAPEUTIC -- Design and Structure -- Mechanism of Action -- Clinical Development and Design -- Target Antigen Selection -- Antibody Selection -- Drug Payload -- Antibody-Drug Conjugation -- ROLE OF MOLECULAR IMAGING IN ADC DEVELOPMENT Pre-clinical Studies of Molecular Imaging of ADCs -- Molecular Imaging in Clinical Development of ADCs -- ErbB2/HER2 -- EGFR -- TAG-72 -- CONCLUSION AND FUTURE DIRECTIONS -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Preclinical Applications with Phage Display-derived Peptides -- Erkki Koivunen1,* -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Perspectives in 11C and 18F Radiochemistry -- Hugo Helbert1,2, Gert Luurtsema1, Rudi A.J.O. Dierckx1,*, Wiktor Szymanski2,3, Ben L. Feringa2 and Philip H. Elsinga1 INTRODUCTION -- 11C -- EXPANDING THE TOOLBOX -- 18F -- TOWARDS ENHANCED BIOORTHOGONALITY -- OUTLOOK -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Introduction to Radionanotargeting in the 1990's: Dosimetry and Optimization of Antisense Oligonucleotide Radiotherapy in Vivo -- Antti Jekunen1,*, Mikko Tenhunen2 and Kalevi Kairemo3 -- INTRODUCTION -- Dose Calculation: From Macro to Micro -- DISCUSSION -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES
The Evolution of Radionanotargeting towards Clinical Precision Oncology is a remarkable book honoring Professor Kalevi Kairemo, who is known among academic and medical circles as a pioneer in novel radiolabeled therapeutics. This festschrift provides an overview of key advances in the field of radionanotargeting, and the directions for future development in patient care. Prof Kairemo's research is based on multiomics, which involves multiple elements: genomics, transcriptomics, proteomics, metabolomics, microbiomics, epigenomics, exposome, imaging, and precision medicine, which is reflected by.