TY - BOOK AU - Straßmann,Sarah TI - Hemisynthesis of phenolic metabolites T2 - Schriftenreihe der Professur für Molekulare Lebensmitteltechnologie SN - 3736965257 AV - QK898 .H465 2021 KW - Polyphenols KW - Metabolites KW - Anthocyanins KW - Electronic Books N1 - Description based upon print version of record; 2; Intro --; Preliminary remarks --; List of abbreviations --; List of publications --; Conferences --; Declaration of contribution as co-author --; Chapter 1 General Introduction --; 1 Polyphenols --; 2 Anthocyanins --; 2.3 Physiological properties --; 3 Synthesis of phase II metabolites --; 3.1 Enzymatic synthesis --; 3.2 Chemical synthesis --; 3.3 Microbial synthesis --; 4 Analysis and Characterization of the metabolites --; 4.1 UV/Vis spectra --; 4.2 Mass spectrometry --; 4.3 Purification --; 5 Aims of the thesis --; Chapter 2 Hemisynthesis of Anthocyanin Phase II Metabolites byPorcine Liver Enzymes; 1 Introduction --; 2 Materials and methods --; 2.1 Chemicals --; 2.2 Isolation of anthocyanins --; 2.3 Preparation of liver fractions --; 2.4 Incubation --; 3 Results and discussion --; 3.1 Methylation --; 3.2 Glucuronidation --; 3.3 Sulfation --; 3.4 Multiple Conversions --; 4 References --; Chapter 3 Chemical Hemisynthesis of Sulfated Cyanidin-3-OGlucosideand Cyanidin Metabolites --; 1 Introduction --; 2 Results and discussion --; 2.1 Cyanidin Sulfates --; 2.2 Cyanidin-3-O-Glucoside Sulfates --; 2.3 Challenges --; 2.4 Human Pilot Study --; 3 Materials and methods --; 3.1 Chemicals; 3.2 Hemisynthesis of Sulfated Metabolites --; 3.3 LC-MS-Analysis --; 3.4 Study Design and Analysis of Urine --; 4 Conclusions --; 5 References --; Chapter 4 Methylation of Cyanidin-3-O-Glucoside with DimethylCarbonat e --; 1 Introduction --; 2 Results and discussion --; 2.1 First Observations --; 2.2 Experimental Design --; 2.3 Increase in Solvation of Anthocyanins --; 2.4 Identification --; 3 Materials and methods --; 3.1 Chemicals --; 3.2 Hemisynthesis --; 3.3 LC-MS Analysis --; 4 Conclusion --; 5 References --; Chapter 5 Concluding remarks --; 1 Impact of contributions; 2 Remaining challenges and future directions --; 3 References --; Summary --; Zusammenfassung --; Acknowledgement; 2; b UR - httpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3104507&site=eds-live&custid=s3260518 ER -