TY - BOOK AU - Johnson,Anne Frances AU - Institute for Laboratory Animal Research (U.S.). AU - Anestidou,Lida ED - Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research (Workshop) TI - Care, use, and welfare of marmosets as animal models for gene editing-based biomedical research: proceedings of a workshop SN - 9780309488518 AV - QL737 .C374 2019 PY - 2019/// CY - Washington, DC PB - National Academies Press KW - Marmosets as laboratory animals KW - Moral and ethical aspects KW - United States KW - Congresses KW - Laboratory animals KW - Gene editing KW - Callithrix KW - Diseases KW - Animal models KW - Animals, Laboratory KW - Disease Models, Animal KW - Animal Welfare KW - Biomedical Research KW - methods KW - Electronic Books N1 - 1; Introduction --; Context for the use of marmosets as animal models --; Ethical considerations --; Current research applications --; Marmoset genomics and genetic diversity --; Marmoset care and management --; Final remarks --; Appendixes; 2; b N2 - The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop UR - httpss://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2243117&site=eds-live&custid=s3260518 ER -