Bacterial membranes : structural and molecular biology /
edited by Han Remaut and Rémi Fronzes.
- Norfolk, UK : Caister Academic Press, (c)2014.
- 1 online resource (513 pages) : illustrations (some color)
Includes bibliographies and index.
Membrane composition and synthesis -- Bacterial cell wall growth, shape and division -- The outer membrane of gram-negative bacteria: lipopolysaccharide biogenesis and transport -- Outer membrane protein biosynthesis -- Bacterial lipoproteins: biogenesis, virulence/pathogenicity and trafficking -- The fascinating coat surrounding mycobacteria -- Protein-lipid interactions -- The role of lipid composition on bacterial membrane protein conformation and function -- Transport across bacterial membranes -- Bacterial ABC transporters: structure and function -- Energy-coupled transport across the outer membrane of gram-negative bacteria -- The permeability barrier: passive and active drug passage across membranes -- Targeting and integration of bacterial membrane proteins -- Envelope-spanning secretion systems in gram-negative bacteria -- Signal transduction across bacterial membranes -- Signalling mechanisms in prokaryotes -- Bacterial membranes in pathogenesis -- Outer membrane-embedded and -associated proteins and their role in adhesion and pathogenesis -- Bacterial membranes as drug targets.
Membranes are pivotal components of life, acting as formidable insulators that demarcate a living cell; generate energy in the form of ion gradients; transport ions, proteins, nucleic acids, nutrients, and metabolites; and provide transduction systems to sense the environment and to communicate with other cells. Membranes also provide shape and structure to cells and are important in cell motility. In addition, they fulfill a scaffolding function for proteins and organelles that interact with the extracellular environment. Written by specialists in the field, this book provides a comprehensive.