TY  - BOOK
AU  - Silverstein,Steven M.
AU  - Moghaddam,Bita
AU  - Wykes,Til
TI  - Schizophrenia: evolution and synthesis 
T2  - Strüngmann Forum reports
SN  - 9781461952350
AV  - RC514 .S359 2013
PY  - 2013///
CY  - Cambridge, Massachusetts, London, England
PB  - The MIT Press
KW  - Schizophrenia
KW  - Etiology
KW  - Clinical medicine
KW  - Decision making
KW  - Mathematical models
KW  - etiology
KW  - Models, Theoretical
KW  - NEUROSCIENCE/General
KW  - Electronic Books
N1  - 2; Schizophrenia --; Heterogeneity --; What kind of a thing is schizophrenia? --; How the diagnosis of schizophrenia impeded the advance of knowledge (and what to do about it) --; What dimensions of heterogeneity are relevant for treatment outcome? --; Which aspects of heterogeneity are useful to translational success? --; Risk and resilience --; How should resilience factors be incorporated in treatment development? --; Insights into new treatments for early psychosis from genetic, neurodevelopment, and cognitive neuroscience research --; From epidemiology to mechanisms of illness --; How can risk and resilience factors be leveraged to optimize discovery pathways? --; Models --; Human cell models for schizophrenia --; How can animal models be better utilized? --; How can computational models be better utilized for understanding and treating schizophrenia? --; How can models be better utilized to enhance outcome? --; Development and treatment --; Why Kraepelin was right --; What will the next generation of psychosocial treatments look like? --; Creative solutions to overcoming barriers in treatment utilization --; What is necessary to enhance development and utilization of treatment?; 2; b
N2  - Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last 50 years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment
UR  - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=664930&site=eds-live&custid=s3260518
ER  -