Pain causes, concerns and consequences / edited by Puneetpal Singh and Monica Singh.

Includes bibliographies and index.

PREFACE ; List of Contributors ; DEDICATION ; Pain: A Clinician's Journey ; INTRODUCTION; PART 1; Pain: a Clinician's journey; Pain; A Theoretical and Applied, Integrative Clinical and Research Understanding; CONCLUSION; PART 2; The Clinician Detective: Applying the Clinician's Journey to Patient Management.; CONFILICT OF INTERST; ACKNOWLEDGEMENT; REFERENCES; Functional Brain Circuitry in Central Post-stroke Pain ; INTRODUCTION; 1. CLINICAL SYMPTOMS OF CENTRAL POST-STROKE PAIN; 2. PATHOGENESIS-RELATED HYPOTHESES OF CENTRAL POST-STROKE PAIN; 2.1. Central Disinhibition.

2.2. Central Imbalance2.3. Central Sensitization; 3. FUNCTIONAL BRAIN ACTIVITY MAPPING; 3.1. Human Neuroimaging of Central Post-stroke Pain; 3.2. Animal Neuroimaging of CPSP; 3.3. 14C] Iodoantipyrine Data and Region-of-Interest Analysis of CPSP in Animal Models; 4. NEURAL CORRELATIONS AND FUNCTIONAL NETWORKS IN THE BRAIN; CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; The Role of Psychological Factors in Cardiac and Non-Cardiac Chest Pain ; INTRODUCTION; CARDIAC CHEST PAIN (CCP); Epidemiology; Etiology; Cardiac Chest Pain and Mechanism of Pain; Myocardial Ischemia Syndrome.

Dissecan Aortic Aneurysm and Mechanisms of PainEndothelial Dysfunction and the Impact of Psychological Factors; Psychological Etiology; CCP Outcomes and Psychological Distress; CCP and Psychotherapy; The Indications for Psychotherapy and Hypnotherapy; NON-CARDIAC CHEST PAIN (NCCP); Epidemiology; Etiology; Psychological Etiology; Differential Diagnosis; Differentiated Impact of Pain with Organic or Psychological Origin; NCCP Outcomes and Psychological Distress; NCCP and Psychotherapy; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Genetic Explorations of Pain ; INTRODUCTION.

1. TRANSDUCTIONHeat Pain; Mechanical Pain; Cold Pain; Chemical Stimuli; 2. CONDUCTION; 3. TRANSMISSION; 4. MODULATION; CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Non-Pharmacological Treatment Options for Coexisting Chronic Non-Cancer Pain and Substance Use Disorder ; INTRODUCTION; The Scope of the CNCP Problem; The Patient with CNCP and SUD; An Approach to the Patient with CNCP and SUD; History of Present Illness (HPI); Other Factors; Physical Exam; Potential Treatments; Movement; Energy Therapies; Psychosocial Treatments; Other Treatments.

Treating the patient using alternative techniquesFinal considerations; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; MicroRNAs: The Tiny Robust Players Unraveling the Multifaceted Channels of Pain ; INTRODUCTION; Pain; MicroRNA; Biogenesis of MiRNA and their Mechanism of Action; Expression Profile of MiRNAs in Different Animal Models of Pain; Regulation of MicroRNAs in Peripheral Somatic Sensory Neurons; Translational aspect of MiRNA Biology in Pain Therapeutics; Prediction and Experimental Validation of MiRNA Targets; Roadblocks in Translating MiRNA Biology to Pain Therapeutics.

CONCLUDING REMARKS AND FUTURE PERSPECTIVES.

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