Campylobacter ecology and evolution /edited by Samuel K. Sheppard ; Guillaume Méric ; associate editor.

Includes bibliographies and index.

In this book, internationally recognised experts critically review and provide novel insights into important aspects Campylobacter research. The book is divided into four sections: Mechanisms of evolution; Adaptations to host colonisation; Molecular epidemiology; and Ecology in poultry. The topics covered range from the mechanisms of evolution through the processes of host colonisation and within host adaptation, and epidemiology to considerations of their broader biochemical and ecological properties. An important resource summarising our current knowledge of Campylobacter ecology and evoluti.

Current books of interest; Contributors; Foreword; Preface; Part I: Mechanisms of Evolution; 1: A Candidate Hopeful Monster in the Genus Campylobacter; Introduction; Hybridization by horizontal gene transfer; 2: Learning About Recombination in Campylobacter; Introduction; Estimating recombination from population data; Estimating recombination from closely related isolates; Discussion; 3: Within-host Evolution of Campylobacter jejuni; Introduction; Phenotypic changes of Campylobacter jejuni after host passage; Genotypic changes of Campylobacter jejuni during host passage; Conclusions

Future studies4: Concerted Evolution in Campylobacter jejuni and Campylobacter coli; Concerted evolution; Duplicated genes in Campylobacter; Unresolved questions; 5: Genome and Transcriptome Evolution in the Genus Campylobacter; Introduction; Characteristics of Campylobacter genome sequences; Transcriptome evolution in the genus Campylobacter; Conclusions; 6: Repetitive DNA: A Major Source of Genetic Diversity in Campylobacter Populations?; Introduction; Types, prevalence and mutability of SSRs in Campylobacter genomes; Variation in SSRs has functionally important phenotypic effects

Combinatorial consequences of multiple phase-variable genesInfluence of mutational, selective and population forces on the diversity of phase-variable genotypes; Modelling phase-variable genes and selection for mutational rates; Experimental issues connected with phase variation; Summary; Future perspectives; Part II: Adaptations to Host Colonization; 7: Campylobacter Strategies for Colonizing the Host Gastrointestinal Tract; Introduction; Carbon sources utilized by Campylobacter to support growth in vivo; Mucins and the mucous layer; Conclusions and future trends

8: The Intricate Relationship Between Campylobacter and MucusThe stucture and function of intestinal mucus; The ecology of C. jejuni in intestinal mucus; Mucus as a source of glycans; Campylobacter jejuni commensalism in chickens; Conclusions and future directions; 9: Campylobacter Association with the Human Host; Introduction; Adhesion, invasion and translocation; Bacterial factors influencing adhesion and invasion of C. jejuni; Do all campylobacters invade to the same extent?; Conclusion; 10: Siderophore-mediated Iron Acquisition for Campylobacter Infection; Introduction

Iron sources in the intestine: an ecological viewEnterobactin-mediated iron acquisition; Salmochelin-mediated iron acquisition; Hydroxamate siderophore-mediated iron acquisition; Conclusion and future directions; 11: Genetic Mechanisms Involved in Campylobacter jejuni Survival Under Oxidative Stress Conditions; The C. jejuni survival conundrum; Oxidative stress overview; C. jejuni mechanisms for countering oxidative stress; Oxidative stress regulation in C. jejuni; Discussion and future perspectives; 12: Oxidative Stress Survival During Campylobacter Transmission and Infection

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