MARC details
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05205cam a2200541Mi 4500 |
| 001 - CONTROL NUMBER |
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ocn847625197 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240726105351.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
121019s2013 ctua ob 001 0 eng d |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
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| LC control number |
2012042874 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
E7B |
| Language of cataloging |
eng |
| Description conventions |
pn |
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rda |
| Transcribing agency |
E7B |
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OCLCO |
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OCLCF |
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GPM |
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EBLCP |
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OCLCQ |
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DEBSZ |
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TEFOD |
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YDXCP |
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TOH |
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MEU |
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NT |
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CUX |
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OCLCQ |
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D6H |
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OCLCQ |
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OCLCO |
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OCLCA |
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AGLDB |
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OCLCO |
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OCLCQ |
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OCLCO |
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ICA |
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OCLCQ |
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OCLCO |
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ZCU |
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OCLCO |
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OTZ |
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MERUC |
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OCLCO |
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OCLCQ |
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OCLCO |
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OCLCQ |
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OCLCO |
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OCLCQ |
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OCLCO |
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UX1 |
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OCLCQ |
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OCLCQ |
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U3G |
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OCLCA |
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INARC |
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UKCRE |
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VLY |
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RECBK |
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AJS |
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OCLCO |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9780300195187 |
| Qualifying information |
|
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781443412148 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781299284104 |
| 050 04 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QR502 |
| Item number |
.F383 2013 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
MAIN |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Ingram, Jay. |
| Relator term |
Author |
| 245 10 - TITLE STATEMENT |
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| Title |
Fatal flaws : |
| Remainder of title |
how a misfolded protein baffled scientists and changed the way we look at the brain / |
| Statement of responsibility, etc. |
Jay Ingram. |
| 246 30 - VARYING FORM OF TITLE |
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| Title proper/short title |
How a misfolded protein baffled scientists and changed the way we look at the brain |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
New Haven : |
| Name of publisher, distributor, etc. |
Yale University Press, |
| Date of publication, distribution, etc. |
(c)2013. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource (viii, 282 pages) : |
| Other physical details |
illustrations |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
data file |
| Source |
rda |
| 520 0# - SUMMARY, ETC. |
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| Summary, etc. |
"Discovered and identified as the cause of mad cow disease only three decades ago, the prion is a protein molecule that, when misshapen in the brain, becomes fatal. Novel and controversial, prions have provoked a scientific revolution. They challenge the very foundations of biology: A disease-causing entity with no genetic material at all? A molecule capable of infecting, multiplying, and killing? This book recounts the birth of prion science and the imaginative detective work scientists have undertaken as they struggle to find the answers to devastating brain diseases from mad cow and Creutzfeld-Jakob disease to Parkinson's, Alzheimer's, Lou Gehrig's, and others. As in each of his best-selling books, Jay Ingram here makes complex scientific concepts accessible and shows how little-known events may have profound significance. He describes the development of prion science as a rough-and-tumble affair, with rivals, eccentrics, interfering governments, and brilliantly creative people all playing salient roles. Weaving biology, medicine, human tragedy, discovery, and bitter scientific competition into his account, he reveals the stunning potential of prion science, whose discoveries may unlock the answers to some of humankind's most destructive diseases"--Provided by publisher. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographies and index. |
| 505 00 - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
The mystery of kuru : a disease like no other -- |
| Title |
Barflies and flatworms : how speculation and pure chance advance a new science -- |
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Cannibalism : an answer guaranteed to stir things up -- |
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Igor and Bill : the discoveries that bring kuru to world attention -- |
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The life of a cell : a miraculous, and often precarious, complexity -- |
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The death of a cell : by subterfuge, piracy, or out-and-out assault -- |
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When is a virus not a virus? : when a disease-causing agent reproduces without genes -- |
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Creutzfeldt-Jakob disease : waking up to the potential of a devastating affliction -- |
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Magnificent molecules : the proteins that make life possible -- |
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Protein origami : building the gothic cathedrals of life -- |
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Stanley Prusiner's Heresy : an infectious agent that's a protein and nothing but -- |
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An infectious idea : the campaign for the minds of researchers -- |
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A portrait of the prion : and the experiments that point to their role in the human brain -- |
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Mad cow disease : the uncertain ground where politics and science intersect -- |
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Mad cow in humans : no barrier after all -- |
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The Americas : mad mink, then cows -- |
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Into the wild : deer, elk, moose, and caribou -- |
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Origins : attempting to find where prions come from -- |
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Cats but not dogs : when prions jump the species barrier -- |
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Alzheimer's disease : plaques and tangles but so far no prions -- |
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Parkinson's disease : looking more and more like a prion disease -- |
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Lou Gehrig's disease : the emerging picture of a prion-like process in ALS -- |
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Chronic traumatic encephalopathy : the athletes' plague -- |
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And in the end ... |
| 530 ## - COPYRIGHT INFORMATION: |
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| COPYRIGHT INFORMATION |
COPYRIGHT NOT covered - Click this link to request copyright permission: |
| Uniform Resource Identifier |
<a href="b">b</a> |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prions. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prion diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
History. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Central nervous system |
| General subdivision |
Infections. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Proteins. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humanities. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Nervous system |
| General subdivision |
Diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Central nervous system |
| General subdivision |
Diseases. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Diseases. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prion Diseases |
| General subdivision |
physiopathology |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prions |
| General subdivision |
history |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prion Diseases |
| General subdivision |
history |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prions |
| General subdivision |
pathogenicity |
| 655 #1 - INDEX TERM--GENRE/FORM |
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| Genre/form data or focus term |
Electronic Books. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=568229&site=eds-live&custid=s3260518">https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=568229&site=eds-live&custid=s3260518</a> |
| -- |
Click to access digital title | log in using your CIU ID number and my.ciu.edu password |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Online Book (LOGIN USING YOUR MY CIU LOGIN AND PASSWORD) |
| DONATED BY: |
|
| VENDOR |
EBSCO |
| Classification part |
QR |
| PUBLICATION YEAR |
2013 |
| LOCATION |
ONLINE |
| REQUESTED BY: |
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NFIC |
| Source of classification or shelving scheme |
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| 994 ## - |
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92 |
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NT |
| 902 ## - LOCAL DATA ELEMENT B, LDB (RLIN) |
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| a |
1 |
| b |
Cynthia Snell |
| c |
1 |
| d |
Cynthia Snell |