Sarcoma oncology : a multidisciplinary approach / edited by] Raphael E. Pollock, R. Lor Randall, Brian O'Sullivan.

Includes bibliographies and index.

Section 1. Overview: epidemiology, pathology, imaging, staging, and prognosis. Environmental and Inherited Risk Factors in Sarcomas -- Introduction to pathology -- Pathology of soft tissue tumors -- Pathology of bone sarcoma -- Bone and soft tissue tumors: contemporary imaging -- PET imaging of mesenchymal tumors -- Traditional size-based response evaluation criteria in solid tumors and new evidence-based response evaluation criteria (Choi criteria) in sarcoma -- Biopsy techniques -- Soft tissue sarcoma staging and nomograms -- Section 2. Sarcoma treatment modalities. Sarcoma surgery: purpose and role relationship to other modalities -- Margins and sarcoma resections: what is marginal? -- Surgery of abdominal wall and trunk sarcoma -- Surgical management of upper extremity bone sarcomas -- Surgical management of lower extremity bone sarcomas -- Surgical management of spinal sarcoma -- Surgical treatment of pelvic bone sarcomas -- Isolated limb perfusion with melphalan and TNF-a in the treatment of extremity sarcoma -- Surgical treatment of sarcomatous lung metastases -- Composite tissue reconstruction after sarcoma resection -- External beam/intensity modulated radiotherapy -- Intraoperative irradiation -- Soft tissue sarcoma brachytherapy -- Particle beam therapy for sarcoma -- Hyperthermia in sarcoma treatment -- Chemotherapy for soft tissue sarcomas: contemporary approaches -- Personalized molecular therapeutics for sarcomas -- Sarcomas of the breast -- Sarcomas of the head and neck -- Section 3. Multidisciplinary care. Genitourinary sarcomas -- Multidisciplinary management of retroperitoneal sarcoma and relapse -- Sarcoma of the heart and great vessels -- Section 4. Specific histologies. Chest wall sarcoma -- Desmoid tumors: a treatment algorithm according to biological behavior? -- Dermatofibrosarcoma protuberans -- Kaposi's sarcoma -- Gastrointestinal stroma tumor: contemporary understanding and management -- Biology of GIST -- Medical management and treatment of recurrent gastrointestinal stromal tumor -- Surgical management of gastrointestinal stromal tumor (GIST) -- Malignant peripheral nerve sheath tumor -- Osteosarcoma: a multidiscplinary approach -- Ewing sarcoma family of tumors -- Chondrosarcoma -- Chordoma -- Rhabdomyosarcoma -- Liposarcoma -- Leiomyosarcoma -- Undifferentiated pleomorphic sarcoma or malignant fibrous histiocytoma -- Angiosarcoma -- Hemangioendothelioma -- Solitary fibrous tumors in the twenty-first century: a clinical and pathologic update -- Clear cell sarcoma -- Alveolar soft part sarcoma -- Synovial sarcoma -- Epithelioid sarcoma --

Section 5. Relapsed sarcoma. Treatment-induced sarcoma soft tissue and bone sarcomas -- Locally recurrent extremity soft tissue sarcoma -- Section 6. Additional considerations. Chemotherapy for palliation -- Palliative care for advanced sarcoma patients -- Palliation for soft tissue sarcomas -- Cost-effective patient surveillance after sarcoma treatment -- Sarcoma survivors -- Long-term consequences of systemic therapies in sarcoma -- Long-term complications associated with radiation therapy in soft tissue sarcoma management -- Outcome measures in musculoskeletal oncology -- Patient advocacy in sarcoma -- The role of the internet in sarcoma care -- Section 7. Laboratory research. Sarcoma cancer stem cells -- Genetically engineered mouse models of sarcoma -- Molecular profiling of sarcomas -- Recent advances in the characterization of mesenchymal tumors: from sarcoma genomics to targeted therapies -- Telomere maintenance mechanisms -- Tumor microenvironment cross-talk.

"Sarcoma Oncology: A Multidisciplinary Approach is a comprehensive textbook that addresses the entire spectrum of the subject from epidemiology to laboratory research in the biology of sarcomas. Chapters contributed by an international group of highly regarded specialists cover the epidemiology and pathology of sarcomas; diagnostic imaging and biopsy techniques; staging and prognosis: surgery of sarcomas in extremity soft tissue, abdominal wall and trunk, and skeletal bone; hyperthermia in sarcoma treatment; isolated limb perfusion; surgery for metastases; reconstructive surgery; radiation therapy; systemic chemotherapy; multidisciplinary care; treatment-induced sarcoma; pain management in sarcoma; and basic research including molecular biology and mouse models"--Publisher's description.

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